atai Life Sciences
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https://atai.life/
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About atai Life Sciences

atai Life Sciences is a clinical-stage biopharmaceutical company dedicated to transforming the treatment of mental health disorders. Founded in 2018, atai focuses on acquiring, incubating, and efficiently developing innovative therapeutics for conditions such as depression, anxiety, and addiction. Their diverse pipeline includes programs like RL-007 for cognitive impairment associated with schizophrenia and GRX-917 for anxiety disorders. By pooling resources and best practices, atai aims to responsibly accelerate the development of new medicines, striving to heal mental health disorders so that everyone, everywhere can live a more fulfilled life.

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Atai Life Sciences Is Bringing DMT To Alcohol Use Disorder
2025-01-28 8:01
  • atai Life Sciences reported promising Phase 2a results for BPL-003, a synthetic intranasal 5-MeO-DMT formulation, showing a single dose reduced alcohol use in patients with moderate to severe alcohol use disorder (AUD), with 50% maintaining complete abstinence for 12 weeks
  • 5-MeO-DMT, a fast-acting psychedelic compound, is known for inducing short but profound experiences, and BPL-003 is engineered to deliver these effects with a quick in-clinic duration of under two hours, making it more practical for therapeutic use
  • The study reinforces 5-MeO-DMT’s potential in addressing mental health and substance use disorders by rapidly altering cognition and behavior, with no severe adverse effects observed, and further research planned for both AUD and treatment-resistant depression in 2025
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